Hypoxic Pulmonary Vasoconstriction

Cellular and Molecular Mechanisms
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(590 Seiten)
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ISBN-13:
9781402078583
Einband:
PDF
Seiten:
590
Autor:
Jason X.-J. Yuan
Serie:
Developments in Cardiovascular Medicine
eBook Typ:
PDF
eBook Format:
PDF
Kopierschutz:
Adobe DRM [Hard-DRM]
Sprache:
Englisch
Beschreibung:

Complete reference on hypoxic pulmonary vasoconstriction and hypoxia-mediated pulmonary hypertension.Can be utilized by the physician-scientist and researcher in the laboratory as both a technical manual and reference.Designed for clinicians to guide and improve clinical treatment and diagnosis of patients with hypoxia mediated pulmonary vascular disease and right heart failure.
Complete reference on hypoxic pulmonary vasoconstriction and hypoxia-mediated pulmonary hypertension.Can be utilized by the physician-scientist and researcher in the laboratory as both a technical manual and reference.Designed for clinicians to guide and improve clinical treatment and diagnosis of patients with hypoxia mediated pulmonary vascular disease and right heart failure.
"Hypoxic Pulmonary Vasoconstriction: Cellular and Molecular Mechanisms will provide a timely and long lasting guide for investigators in the fields of cardiovascular physiology and pathophysiology, pulmonary vascular disease, high-altitude physiology and medicine. In addition, it provides a solid scientific foundation for subsequent applications in clinical practice. The volume is divided into eight sections: • Physiology and Pathophysiology of HPV • Role of Intracellular Ca2+ and Ca2+ sensitivity in HPV • Role of Ion Channels in HPV• Role of the Endothelium in HPV • Mechanisms of Oxygen Sensing in the Pulmonary Vasculature • OxygenSensing Mechanisms in other Organs and Tissues • Pathology and Mechanisms of Hypoxia-Induced Pulmonary Hypertension • Experimental Models for the Study of HPV State-of-the-art findings relevant to cellular and molecular processes of hypoxic pulmonary vasoconstriction as well as knowledge regarding etiological mechanisms and experimental therapeutics are well covered and complete the overview this volume provides. Experienced basic science investigators in the research fields of hypoxic cardiopulmonary physiology, pathophysiology and pulmonary diseases; clinicians; physician-scientists involved in pulmonary or critical care medicine; cardiology; cardiothoracic surgery; environmental medicine; and sports medicine will find Hypoxic Pulmonary Vasoconstriction: Cellular and Molecular Mechanisms a useful reference. The Editor, Jason X.-J. Yuan, MD, PhD is a Professor of Medicine; Division of Pulmonary and Critical Care Medicine; Department of Medicine at the University of California at San Diego, in San Diego, California."
  • List of Contributors.
  • Preface.
  • I: Physiology And Pathophysiology Of Hypoxic Pulmonary Vasoconstriction:- C.A. Hales, C.A. Dawson, Yuan-Cheng Fung, Wei Huang.
  • II: Role Of Intracellular Ca2+ And Ca2+ Sensitivity In Hypoxic Pulmonary Vasoconstriction:- Wei-Min Zhang, C.V. Remillard, J.S.K. Sham, J.-P. Savineau, S. Bonnet, R. Marthan, A.M. Evans, M. Dipp, T.P. Robertson, I.F. McMurtry.
  • III: Role Of Ion Channels In Hypoxic Pulmonary Vasoconstriction:- S.V. Smimov, R. Moudgil, E.D. Michelakis, S.L. Archer, H. Patel, C.V. Remillard, J. X.-J. Yuan, A.M. Gurney, Lih-Chyuan Ng.
  • IV: Role Of Endothelium In Hypoxic Pulmonary Vasoconstriction:- J.P.T. Ward, P.I. Aaronson.
  • V: Mechanisms Of Oxygen Sensing In The Pulmonary Vasculature:- L.A. Palmer, S.A. Gupte, M.S. Wolin, N.S. Chandel, A. Olschewski, E.K. Weir, S. McMurtry, E.D. Michelakis, A.M. Evans.
  • VI: Oxygen-Sensing Mechanisms In Other Organs And Tissues:- A. Gorlach, H. Acker, T. Kietzmann, J. López-Barneo, P. Ortega-Saenz, M. Garcia-Fernandez, R. Pardal, R.J. Thompson, C.A. Nurse, L. Conforti, D.E. Millhorn.
  • VII: Pathology And Mechanisms Of Hypoxia-Induced Pulmonary Hypertension:- M. Rabinovitch, I.F. McMurtry, N.R. Bauer, S.A. Gebb, K.A. Fagan, T. Nagaoka, M. Aka, T.P. Robertson, A.L. Zaiman, R.M. Tuder, M.G. Frid, N.J. Davie, K.R. Stenmark, S.H. Abman, R.H. Steinborn, B. Raffestin, S. Adnot, S. Eddahibi, M.N. Gillespie, K.A. Ziel, M. Ruchko, P. Babal, J.W. Olson, M.R. Karamsetty, J.C.Leiter List of Contributors -Preface -Physiology And Pathophysiology Of Hypoxic Pulmonary Vasoconstriction -Role Of Intracellular Ca2+ And Ca2+ Sensitivity In Hypoxic Pulmonary Vasoconstriction -Role Of Ion Channels In Hypoxic Pulmonary Vasoconstriction -Role Of Endothelium In Hypoxic Pulmonary Vasoconstriction -Mechanisms Of Oxygen Sensing In The Pulmonary Vasculature -Oxygen-Sensing Mechanisms In Other Organs And Tissues -Pathology And Mechanisms Of Hypoxia-Induced Pulmonary Hypertension -Experimental Models For The Study Of Hypoxic Pulmonary Vasoconstriction -Index

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